Sentence examples for a master cell from inspiring English sources

Their building block is the stem cell, a "master cell" which can, in certain conditions, divide to produce different types of body tissue.

As FoxM1 is a master cell cycle gene for many cell cycle proteins, we deleted FoxM1 from DP thymocytes by crossing floxed FoxM1 mice [23] to two different T cell specific Cre transgenic mice (lck-Cre and CD4-Cre) [24], [25].

Given the role of FoxM1 as a master cell cycle regulator in other cell types [23], [28], [33], including mature T cells (this report), it is surprising to see that cyclin B1 is the only protein whose expression is being affected in FoxM1-deficient DP thymocytes.

Additionally, a master cell bank is available for manufacturing of clinical material.

The clinical-grade AaPCs are genetically modified K-562 cells that are available as a master cell bank.

The model assumed that enough cells are available from a master cell bank to seed the T-flasks at stage 1.

It should be noted that ESRP1 is a master cell-type-specific splicing regulator critical for maintaining the epithelial cell identity and has been implicated in a variety of developmental and disease processes [ 46].

Target prediction showed that BMI1, a transcription factor necessary for hematopoietic stem cell (HSC) and leukemia stem-cell self-renewal (27, 28), is the putative target of both miR-27a and miR-128b, while E2F1, a master cell-cycle regulator, is the target of miR-223 (29).

Here we show that multiple cellular products currently being considered for therapy can be generated from a single master cell bank of this or any other clinically compliant iPSC line.

IFC acts as an 'apoptotic master cell', with each IFC exerting a life or death control over 20 neighbouring target TCs.

They have also been manufactured as a clinical grade master cell bank and used in a first-in-human safety study.