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Isolates from single patients were variable for many traits commonly taken as a marker of variation in RpoS levels (breadth of carbon source utilization, motility, H2O2 and acid sensitivity, glycogen production, and the red dry and rough morphotype).
Moreover, we suggested that metastatic synchronization can be quantified by the standard deviation of size and number of metastases at time of first recurrence, as a marker of variation in the metastatic pattern.
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With the current state of knowledge, the opening and/or closure of the BHC in most species seems to be a marker of variations in the dosage of Shh and Shh pathway-related genes during cranial base and midline morphogenesis.
In addition, we run sensitivity analysis with additional adjustment for the time of the day of urine collection as a marker of diurnal variation.
It has been demonstrated that SVV (as a marker of respiratory variation in SV) could predict fluid responsiveness in patients receiving mechanical ventilation [ 32- 36].
Therefore the interaction that we have observed between this polymorphism, which may well be nothing more than a marker of other mitochondrial variation and have no functional relevance specifically, and alcohol consumption on breast cancer risk could be due to other mitochondrial polymorphisms which occur in common with A10398G.
In this respect, ΔPOP is potentially a marker of respiratory stroke volume variation.
On the other hand, rMSSD reflects short-term variability seen with respiration at rest and is thought to be a marker of the parasympathetic nervous system variation (Task Force 1996).
The analysis of HRV has been used for evaluate the autonomic cardiac activity in numerous pathophisyologic conditions [ 1- 9]: an impaired heart rate variation is a marker of autonomic neuropathy [ 10, 11] as in diabetic subjects [ 12- 16].
Alternatively, we cannot rule out the possibility that the plasma Aß1-42/Aß1-40 ratio is merely a marker of other parameters involved in BP variations or that the plasma Aß1-42/Aß1-40 association with BP is a consequence of BP variations by themselves.
Accurate assignment of exposure depends on the availability of effective markers of variation in exposure, whatever the underlying diversity of exposures may actually be.
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