Sentence examples for a marker of pathological from inspiring English sources

In order to examine whether PGP 9.5 is a marker of pathological angiogenesis, we also stained wild type lung sections where staining was found exclusively in large vessels but not in capillaries (Figure S6E) in line with a recent publication showing expression of PGP 9.5 in human carotid arteries [33].

Furthermore, offspring of obese dams had increased p38MAPK, a marker of pathological cardiac hypertrophy (58).

As a marker of pathological vascular damage, endothelial dysfunction was associated with polycystic ovary syndrome, as well.

We also used the phospho-dependent antibody PHF1 (pSer396/pSer404), a marker of pathological phosphorylation of endogenous Tau. PHF1 showed exclusively axonal immunoreactivity of mossy fibers in the stratum lucidum but not in control littermates.

These data suggest that synaptic dysfunction can occur without the presence of Lewy bodies per se and that perhaps using the Lewy body alone as a marker of pathological progression is not sufficient to predict the spread of disease.

In conclusion, our data suggests that the presence of immunoproteasomes in the CNS could be a marker of a pathological scenario involving neuroinflammation (autoimmunity, neurodegeneration but also ageing) [6], [7], [47], therefore putting immunoproteasome forward as potential candidate for future therapeutic approaches [48], [49], [50], [51], [52].

Our data support the predictive role of ETAR overexpression as a marker of adverse pathological response to chemotherapy treatment in breast cancer.

It has not yet been determined whether anisocytosis is the cause of the poorer prognosis observed among these patients or if it is simply a marker of multiple pathological states connected with said prognosis.

Past research has shown that variations in electrical impedance among tissues can be a good marker of pathological changes in human and animal subjects [ 2– 11].

These findings indicated that loss of TACSTD2 could promote SCC progression and treatment resistance through attenuating chemotherapeutic reagent-induced apoptosis through TAp63, and TACSTD2 could be used as a marker for pathological grading of SCC.

These data demonstrated that gradual loss of TACSTD2-positive epithelial cells was associated with SCC progression, indicating that loss of TACSTD2 may have a critical role in SCC progression and suggesting that TACSTD2 could be used as a marker for pathological grading of SCC.