The phrase "a markedly new" is correct and usable in written English.
It can be used to describe something that is significantly different or innovative compared to what has been previously known or experienced.
Example: "The research presented a markedly new approach to solving the problem, which had not been considered before."
Alternatives: "a significantly new" or "a distinctly new".
Whether Ms. Rice can begin to achieve it may depend on how well she adapts to a markedly new role, and surmounts problems that have dogged her as national security adviser for the past four years.
The India to which I had recently returned, after more than a decade in America, was a markedly new one: a country where rice fields were giving way to highways, farmland to software complexes, and saris to pants.
It then produced a markedly different new chart, saying it had put those adjustments into the proper years.
This new phase introduced two markedly new characteristics in his work.
"The results of the elections are here, fully reflected in this significantly changed composition of this august house," Mr. Mugabe said today in a markedly conciliatory speech to the new Parliament.
Renewable energy capacity around the world was boosted by a record amount in 2016 and delivered at a markedly lower cost, according to new global data – although the total financial investment in renewables actually fell.
But just the possibility that Wal-Mart might receive the go-ahead to open stores in Los Angeles in 2004 compelled that city's supermarket employee union to accept a management demand to establish a markedly lower pay scale for new hires.
Wayne Lee took her spring collection in a markedly different - and exciting - new direction that looked like the work of a designer who is finding her voice.
Compared with the parental Gefitinib, most of the new compounds show a markedly increased cytotoxicity to cancer cells.
Each new subject inspired a markedly different treatment of pictorial space, one that was usually smaller, clearer or more confined than its predecessor.
Employers sometimes worry that these individuals won't be able to handle new responsibilities in a markedly different work environment.
