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The phrase "a markedly lower level" is correct and usable in written English.
It can be used to describe a significant decrease in quality, quantity, or intensity compared to a previous state or standard.
Example: "The recent study showed that the participants exhibited a markedly lower level of engagement than in previous sessions."
Alternatives: "a significantly reduced level" or "a considerably lower level".
Exact(7)
Those who would be newly eligible for statin therapy include more men than women and persons with a higher blood pressure but a markedly lower level of low-density lipoprotein cholesterol.
It indicates that the language employed in these flagship addresses is of a markedly lower level of sophistication now than it was in the past.
However, the transcript of the ZGA marker gene metallothionein 1A (MT1A) could be detected in two-cell stages of importin α7-deficient embryos, albeit at a markedly lower level than in wildtype.
The strongest differences between spring and fall were seen in TSH, with a markedly lower level in the fall.
Otherwise, HCC cells express integrin α4 at a markedly lower level than integrin α5 (Fu et al, 2010).
4 Although the long-term health risks of e-cigarette use are not yet known, vapourised nicotine products are likely to pose some level of health risk, but a markedly lower level of risk than combusted tobacco products.
Similar(53)
Similarly we note that TK10 cells are as sensitive as MCF7, yet have markedly lower level of metabolism [ 22].
According to Dr. Sabelli, examinations involving hundreds of people showed that when compared to healthy individuals, 70percentt of the depressed patients had markedly lower levels of a brain chemical called 2-phenylethylamine, an amphetamine-like substance.
The Iranian approach emphasises gaining agreement now on that end state - in which Iran would continue to enrich uranium (presumably at markedly lower levels) but as part of a heavily inspected peaceful nuclear programme - so that everyone can understand the direction of travel.
Because Tph1 mice are known to have markedly lower levels of peripheral 5-HT, a logical conclusion is that plasma 5-HT is necessary for the development of dexfenfluramine-induced PAH in these mice.
Interestingly, while apoptosis (measured by annexin V binding) was elevated alongside autophagy (figure 6B,C), there was a degree of mutual exclusivity, in that annexin V+ cells had markedly lower levels of autophagy than non-apoptotic cells.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com