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However, doubling the copy number further from 3 to 6 generated a markedly increased inhibitory effect on vector amplification.
Studies in aged (24-month-old) rats demonstrated a markedly increased sensitivity to the acute effects of parathion but not chlorpyrifos (Karanth and Pope 2000).
There is a markedly increased chance that such companies have also engaged in the practice, making their stocks vulnerable.
RA patients experience a markedly increased frequency of cardiovascular disease.
Stratifying for sex markedly increased the effect sizes, largely because of the different directions of the Cd-related DNA methylation in boys and girls.
Both rapamycin and caffeine led to delayed growth and decreased maximal growth rate, and combination of the two drugs markedly increased these effects (Fig. 5C,D).
The AMD-associated CFH(H402) variant markedly increased this inhibitory effect on microglial cells, supporting a causal link to disease etiology.
Tran et al. prepared a nanoparticle to contain both siRNAs against BRAF and Akt3 which markedly increased the anticancer effect [ 143].
Indeed, very low concentrations of these entry inhibitors markedly increased the antiviral effect of alisporivir by decreasing its IC50 up to 3000-fold.
In that study, when dioxin was administered to mice fed standard mouse diet, abundance of TNF-α mRNA in adipose tissue was markedly increased, and this effect was abolished in AhR deficient mice.
However, co-treatment of A549 cells with TRAIL and AFMC markedly increased the cytotoxic effects of TRAIL in a dose-dependent manner compared to treatment with TRAIL or AFMC alone.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com