Sentence examples for a markedly diminished from inspiring English sources

This results in anoikis, a type of apoptosis characterized by cell detachment, and, consequently, a markedly diminished epidermal turnover time in psoriasis.

Each infant underwent cardiac catheterization to complete the diagnostic evaluations.Significant right ventricular hypertension and normal pulmonary venous return were demonstrated, but a markedly diminished or absent capillary blush phase was noted in each infant.

When stimulated with the beta AR agonist isoproterenol, cells bearing either the wild type or mutant receptors generated cAMP at essentially identical rates for the first 2 min. Cells bearing wild type receptors then showed a rapid desensitization characterized by a markedly diminished rate of cAMP production after the first few minutes of stimulation.

Spleens were also discolored upon visual inspection and exhibited altered architecture upon histological analyses consisting of a markedly diminished red pulp and poorly defined lymphatic nodules (Fig. 3A-D).

In contrast, Tregs obtained from SSc patients all had a markedly diminished suppressive capacity compared to those from healthy donors (Figure 3a) with T regs from lSSc, edSSc and ldSSc suppressing CD4+ effector cell proliferation by, respectively, 28.2%±6.0 (P = 0.0001), 56.0%±8.5 (P = 0.006) and 18.3%±5.2 (P<0.0001).

In contrast, the IV administration of virus resulted in a markedly diminished OVA specific CD8+ T cell response in the liver as detected by tetramer staining (Fig. 1A) with a likewise markedly diminished frequency of CD8+ T cells responding to specific peptide stimulation in vitro with IFN-γ production (Fig. 1B).

A second individual, Patient 8716, a 62 year old white female, presented to the Clinic in 2006 with a complaint of markedly diminished taste sensitivity.

Johnson was perhaps the last to realize that his loss to Willard (which he claimed for ever after to be a thrown fight) had markedly diminished his worth, and he had dwindling creditors to turn to.

Although there will be opposition by players and spectators alike, it is past time for more reasonable minds to recreate the game of football so the contact is markedly diminished to a level that does not result in the morbidity and mortality that have become all-too-common aspects of the sport.

The extent of mucus staining was markedly diminished in a dose-dependent manner in OVA-induced mice treated with SCTE.

Following exposure to extracellular SMase C from S. aureus, the CFTR current was markedly diminished in a time-dependent manner.