The phrase "a marked risk" is correct and usable in written English.
It can be used to describe a significant or noticeable level of risk associated with a particular situation or action.
Example: "Investing in that startup presents a marked risk due to its unstable financial history."
Alternatives: "a significant risk" or "a considerable risk."
There was a knock-on effect on the development of the film genre in the early years of the Federal Republic of Germany, which was characterised by a marked risk aversion.
In the current circumstances, with a marked risk of a double-dip recession, the strength of the recovery should take precedence.
Adhesions are associated with a marked risk of enterotomy jeopardising 19%% and 10 25 % of patients undergoing open and laparoscopic surgery, respectively [12, 13].
In essence, patients classified as responders to lithium stabilization had, according to their course of illness, a marked risk of further recurrences.
A marked risk was observed with parental smoking for SHS exposure at home and with close friends smoking for SHS exposure outside household.
The report showed that among TrialNet participants with two or more autoantibodies, there was a marked risk difference according to the presence or absence of ZnT8A.
Approximately 98% of the participants had depression according to the GDS score and were recorded as having a marked-to-very marked risk of falls.
A PPA z-score of 0 1 indicates mild risk, 1 2 indicates moderate risk, 2 3 indicates high risk, and 3 and above indicates marked risk [ 19].
It thus seems that the marked risk reduction for T2D was driven by the glucose-lowering effect of rosiglitazone/metformin in the first year.
But there is marked risk of some serious side effects like renal, hepatic and gastrointestinal complications with the use of NSAIDs.
There were also marked risk reductions in development of PDR (47%), onset of macular edema (26%), and application of laser therapy (56%) (2).
