Sentence examples similar to a marked requirement from inspiring English sources

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There was, however, a marked PKD2 requirement for TCR induction of mRNAs encoding multiple cytokines and chemokines, like IL-2, -3 and -6, IFN-γ, Ccl (chemokine ligand) 3 or Ccl4 (Table 1 and Supplementary Table S2).

20 21 In order to meet this requirement, a marked increase in stroke volume during early recovery with overshoot appears to be facilitated by both an immediate afterload reduction and a relatively slow decrease in cardiac sympathetic stimulation.

The normalization of serum T3 levels in other studies was reflected in a marked decrease in the requirement for inotropic support, conversion to normal sinus rhythm, and progressively improving clinical course without clinically adverse effects [ 55, 113].

This requirement is a marked difference with respect to the SC proposed by the WHO, which recommends verification as a team.

Thus, a marked difference could be observed between the requirement of Wg signalling in intestinal homeostasis and regeneration.

There was a marked tendency to orient titles, fiction and nonfiction, to the requirements of the school curriculum.

It is a marked change from a year ago.

The 2007 move to scrap the £2m sponsorship requirement for universities, colleges and private schools to run academies prompted a marked expansion in the numbers coming forward.

In mammals, a marked under-representation of introns in the 3'UTRs may be explained by the requirements for nonsense-mediated decay (NMD) [ 38, 39].

A common trait among these pathogens and T. whipplei is a small genome size between 0.93 2.0 Mb, a marked AT nucleotide bias, and the loss of several metabolic pathways, which explains their complex nutritional requirements [ 8, 34- 37].

In the first trimester there is a marked, somewhat paradoxical, decrease in the absorption of iron, which is closely related to the reduction in iron requirements during this period as compared with the non-pregnant state (see below).

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