Sentence examples for a marked problem from inspiring English sources

Combating desertification, a marked problem in arid, semi-arid and other desertification-affected areas of the world, encompasses the management of water resources and the conservation of soil properties.

Cytotoxicity often correlates with a high charge density and is a marked problem with highly cationic PAMAM dendrimers.

However, cytotoxicity of highly cationic dendrimers is a marked problem that hinders their widespread use in drug and gene delivery [ 6, 7].

It is characteristic in NPC that a wider irradiation field is required during RT due to its progression pattern, and mucositis is a marked problem even when RT alone is performed.

That is, among 2123 women not reporting severe pain, but reporting heavy or very heavy periods, 21% and 72% respectively reported their periods a severe or marked problem [ 1].

Autism appears to present a special case where various factors seen operating in the groups listed above can combine to lead to marked problems in this area.

Although it would be expected that secondary care provides implant treatment for those with the most marked problems, this is not necessarily the case.

It is likely that prevalence in Thailand would be higher in 2009: Thailand has experienced a marked increase in problem alcohol use in over the past 10 years, in the context of increased GDP and vigorous alcohol marketing [ 48].

Some, however, worried privately that the mishap reflected a boyish, overeager 42-year-old campaigner, a marked contrast to the problem many bemoaned months ago, that the then-presumptive nominee, Mayor Rudolph W. Giuliani, did not have his heart in the race.

As one contemporaneous journalist observed, "Spider-Man has a terrible identity problem, a marked inferiority complex, and a fear of women.

While, there is a marked decline in the problem since 1998, when mine action commenced, the practice has by no means disappeared in the project areas.