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Here is a simple system that uses a marked set of needles that can fix this problem.
Puncture with this gauge needle results in a marked septic response but with death occurring in 0 10% of animals.
A particularly problematic additional effect is that MO solutions can have a marked tendency to develop small precipitates that clog the needles used to deliver MOs via microinjection.
Next, a 25 gauge B-bevel needle (Unisys Corp., Japan) was inserted until a marked decrease of resistance was noted, followed by the injection of 1 ml of levobupivacaine containing 1 200,000 epinephrine.
It is a marked change from a year ago.
Tattooists themselves say they've witnessed a marked increase in the numbers of customers coming back for a repeat needling.
Sweden provided a marked contrast.
There was often a marked dramatic element.
The skeptic was a marked man.
A marked second, unfortunately, is the atmosphere.
I was now a marked man.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com