Sentence examples similar to a marked necessity from inspiring English sources

Dicer conditional knockouts had largely normal baseline sensory phenotypes but had a marked insensitivity to inflammatory agents both behaviorally and electrophysiologically, demonstrating the necessity of Dicer and small RNAs for normal responses to nociceptive inflammatory stimuli.

It is a marked change from a year ago.

This approach represents a marked change from earlier times when the doctor's beliefs about the value of a drug/intervention were sufficient to establish medical necessity.

Sweden provided a marked contrast.

This is a marked change.

Then came a marked decline.

I'm a marked man.

There was often a marked dramatic element.

The skeptic was a marked man.

A marked second, unfortunately, is the atmosphere.

Flitcroft was a marked man.