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The phrase "a marked modification in" is correct and usable in written English.
It can be used to describe a significant change or alteration in a particular context, such as a process, behavior, or condition.
Example: "The study revealed a marked modification in the participants' behavior after the intervention."
Alternatives: "a significant change in" or "a notable alteration in".
Exact(1)
Unexpectedly, we observed a marked modification in N1E-115 cell size (Fig. 2a and 2c): both HIF2α clones displayed an average 30% increase in cell diameter (p < 0.001), while HIF2α(1 485) cells were 15 to 25% smaller than native or pCDNA3.1-transfected cells (p < 0.001).
Similar(59)
In particular, it has been shown that proteasome blockade by proteasome inhibitors resulted in a marked modification of gene expression and activity of MMPs (upregulation of MMP-1, -3 and downregulation of MMP-2, -9) and TIMPs (downregulation of TIMP-1).
OPN in concentrations from 1.59 to 3.82 μM caused a marked modification of crystal shape with increasing concentration.
The present study, demonstrating significant correlations between age and inflammatory mediators of the eicosanoid and MMP pathways in whole buccal saliva from healthy volunteers, points to a marked modification of the inflammatory state of the oral cavity associated with age.
SuFEx modification of BSA caused a marked change in the pH dependent size and zeta potential of the protein as well as increased the protein's denaturation temperature.
"It's clear we need a marked change in approach.
Ms. Dorfman has seen a marked change in Kerron.
This is a marked change in habits.
Although the principle of isomaltulose action is unquestionable, a more marked modification of the dietary GI may be required to achieve a clinically significant improvement in glycemic control in type 2 diabetic patients.
Data also suggested a marked increase in post-translational modification of proteins such as folding, methylation, and alkylation.
As can be seen from the results reported in Table 5, although decreasing the block dimension P would imply the possibility of embedding more bits in a given HDR image as shown in Table 4, it would also result in an increased probability of detecting a modification in the marked HDR image.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com