The phrase "a marked limitation" is correct and usable in written English.
It can be used to describe a significant or noticeable restriction or constraint in a particular context, such as in assessments or evaluations.
Example: "The study revealed a marked limitation in the sample size, which may affect the reliability of the results."
Alternatives: "a significant limitation" or "a notable restriction".
CHF was firstly identified clinically as being recorded in patient notes as a significant reason for admission, according to the New York Heart Association NYHAA) classification as Class III (marked limitation of activity; comfortable only at rest) or IV (should be at complete rest, confined to bed or chair; any physical activity brings on discomfort and symptoms occur at rest).
The condition was recovered with physiotherapy in one patient followed by arthrofibrosis and marked limitation of wrist movement in the other.
There was marked limitation of the ROM, mostly due to volar skin abrasions with contracted elbow flexors due to the prolonged immobilization period.
The indication for surgery in this group of patients included acquired gait disturbance (obligate out-toeing), marked limitation of hip flexion (<25°) and hip or knee pain that interfered with activities of daily living.
The hip showed about forty degrees of flexion but marked limitation of abduction and rotation.
NYHA Class I referring to no limitation, Class II to slight limitation, Class III to marked limitation in patient's physical activity respectively.
Despite repeated surgical debridement and manipulative arthrolysis, marked limitation of joint motion (30 degrees of flexion contracture and 110 degrees of further flexion) remained.
Post-procedure, ten patients (50%) had no functional limitations of activities, seven patients (35%) had minimal limitation of functional activities, two patients (10%) had moderate functional limitation, and one patient (5%) had marked limitation of functional activities (Fig. 3).
Dyspnoea was grouped according to the New York Heart Association (NYHA) functional classification: NYHA 1 (no symptoms and no limitation in ordinary physical activity); NHYA 2 (mild symptoms and slight limitation during ordinary activity); NYHA 3 (marked limitation in activity due to symptoms, comfortable only at rest); or NYHA 4 (severe limitations, experiences symptoms even while at rest).
This classification scheme divides patients into four groups: Group 1: ordinary activity which does not cause angina such as walking and climbing stairs; Group 2: slight limitation of ordinary activity; Group 3: marked limitation of ordinary physical activity; Group 4: inability to carry on any physical activity without discomfort [ 16].
