At either extreme, we see a marked drop in effectiveness.
It also heralded a marked drop in the temperature.
As the eclipse progresses, you'll notice a marked drop in temperature.
She has suffered a marked drop in the number of people viewing her as "honest and trustworthy".
Leading charities have noted a marked drop in the number of children being put up for adoption.
"All the participants showed a marked drop in blood levels of indinavir after taking St .John's wort.
Sherry Cooper, chief economist at Nesbitt Burns Securities, said: "Aside from a marked drop in inventories, every component flashed strength.
Yet Manzhouli shopkeepers complain of a marked drop in customers this year, blaming the state of the Russian economy.
Particularly, silencing of RHOA caused a marked drop in both acinar size and circularity (Figures 3c and d).
In the last decade, many countries in Africa have seen a marked drop in the practice of cutting.
Separate data, produced by industry trade body the British Retail Consortium (BRC), also recorded a marked drop in footfall in March.
