Sentence examples for a marked difficulty from inspiring English sources

If we plot (varphi_{omega}) it will resemble the Euclidean Bessel-kind covariance functions; only there is a marked difficulty in dealing with the growth at infinity of these functions, which accounts for some (not all, of course) of the many difficulties Harish-Chandra and Helgason had to overcome in developing harmonic analysis on (mathbb{D}).

MH's most pronounced aphasic symptom, both initially and residually, was a marked difficulty in confrontation naming in both languages.

RA is an 87-year-old male with marked difficulty in walking due to some degenerative joint disease involving neck and spine.

First, bipolar disorder is often associated with marked difficulty in establishing and maintaining relationships [ 39- 41].

Bipolar disorder is characterized by marked difficulty in regulating the pursuit of goals (Johnson, 2005), with the onset of manic and depressive episodes linked to the attainment and failure to obtain goals, respectively (Johnson et al., 2008).

Given the predominance of rodent models of human disease and the marked difficulty in performing transplantation experiments in these models, it remains unknown whether Tsc1 or Tsc2 mutant cells can produce the focal brain hamartomas that are almost universally seen in patients with TSC.

Bibliotherapy is suitable for people with moderate depression, but is unsuitable for individuals with severe depression [ 47] because of marked difficulties in concentrating and cognitive impairment, and a greater suicide risk [ 48].

According to its definitions, which can be found here, the category includes post-traumatic stress syndrome and phobias or compulsions that result in "marked difficulties" with working or living in society, or "complete inability to function independently outside the area of one's home".

A new report into what children are reading at school shows a "marked downturn in difficulty of books at secondary transfer", it was revealed today.

Adhesive capsulitis (AC) of the shoulder manifests as an insidious onset of shoulder pain and the progressive limitation of active and passive shoulder movement, resulting in a marked disability and difficulty with daily activities.

In the present study, irritability, feeding difficulties and a marked rise in CRP were important in establishing the diagnosis of sepsis in the newborn.