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The phrase "a marked destabilization of" is correct and usable in written English.
It can be used in contexts discussing significant changes or disruptions in stability, often in political, economic, or social discussions.
Example: "The recent events have led to a marked destabilization of the region, affecting both security and economic conditions."
Alternatives: "a significant disruption of" or "a pronounced instability in".
Exact(1)
This was in agreement with analysis of the disaggregation events during blood flow, pointing to a marked destabilization of the thrombi formed in the presence of ticagrelor or cangrelor (Fig. 7E).
Similar(59)
In order to support the effect of this newly revealed pertuzumab-induced trastuzumab epitope, we have constructed an in silico truncated form of Her2, where this β-hairpin has been deleted (T323C-AEDG-T328C), and we find that the binding energetics undergo a marked destabilization (Table 1).
Regardless of the exact mechanisms involved, the strong impairment of AUG recognition in vivo and marked destabilization of the PIN state in vitro conferred by E144R dramatically illustrates that a 40S ribosomal protein functions as an equal partner with soluble initiation factors in ensuring efficient and accurate start codon recognition.
However, under hyperoxic conditions deletion of astrocyte-derived VEGF led to a pronounced destabilization of the retinal vasculature.
The results showed a pronounced destabilization of the aging epigenome, which was characterized by a widespread loss of methylation marks.
However, it is clear that, unlike the situation with apoE4 where simultaneous destabilization of both domains leads to a marked enhancement of lipid binding (emulsion binding and DMPC MLV solubilization), a change in stability of the C-terminal domain alone has relatively minor consequences for such lipid interactions.
Let (mathsf {B}) be a marked basis of (Bbbk ^X).
Clinical examination revealed a marked swelling of the knee.
There has always been a marked lack of evidence.
What if weariness is a marked sign of hopefulness?
The 21st century has been a marked period of personalization and humanization.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com