The phrase "a marked deficit of" is correct and usable in written English.
It can be used to describe a significant lack or shortage of something, often in a formal or academic context.
Example: "The study revealed a marked deficit of resources available for mental health support in the community."
Alternatives: "a significant lack of" or "a considerable shortage of".
With respect to small-animal imaging, however, there still seems to exist a marked deficit of validation studies demonstrating the quantitative accuracy of ASL, and reliable data are scarce [7, 13, 14].
Immune-related gene families involved in recognition, signal modulation, and effector systems show a marked deficit of orthologs and excessive gene expansions, possibly reflecting selection pressures from different pathogens encountered in these insects' very different life-styles.
However, a marked deficit of heterozygotes at a SNP can also arise if genotyped subjects originate from two non-interbreeding populations, a phenomenon sometimes called the Wahlund effect (17).
Despite this endorsement of the importance of health advocacy, and the related self-reported competencies, there was a marked deficit of self-reported engagement in health advocacy activities within the resident cohort.
Finally, the strongly disordered region in Sm B/B' from residues 51 240 in Fig. 2d corresponds to a marked deficit of potential T cell candidates in the same region in Fig. 4d compared to the number of potential epitopes in the first 50 residues.
For example, analysis of the complete immune system of A. gambiae results in the discovery of a marked deficit of orthologues due to gene loss and excessive expansion of some specific genes, which is significantly different from that of D. melanogaster.
The patients also showed a marked deficit on the RBMT (P = 0.001, Mann–Whitney U-test) relative to the score of the normal control group.
Among persons with CKS who died of other causes, an excess for lymphoid malignancies emerged (SMR=4.40) (chronic lymphocytic leukaemia (11.03), non-Hodgkin's lymphoma (4.22), Hodgkin's lymphoma (11.80), and multiple myeloma (2.3)), balanced by a deficit for all solid cancers (0.56), with a marked deficit for lung cancer (0.41).
A marked deficit in one of these factors may be sufficient to increase the risk of falling; however, a combination of minor or moderate impairments in multiple physiological domains may also increase the risk of falling.
ITC lesions caused a marked deficit in the expression of extinction that correlated negatively with the number of surviving ITC neurons (Likhtik et al., 2008).
In the extinction trial, however, HAB rats showed a marked deficit in the attenuation of freezing responses to repeated auditory conditioned stimulus presentations as compared with LAB rats, which exhibited rapid extinction.
