However, the concentration of ATP is not a good guide to the role of bioenergetic failure because even when there is a marked increase in consumption of ATP, as occurs during normal exercise, the concentration of ATP usually stays constant.
With urbanization (or migration to Western environments), there is a marked increase in consumption of energy rich foods, a decrease in energy expenditure (through less physical activity) and a loss of the traditional social support.
Following the generally upward trend in successive birth cohorts, there is a marked decrease of consumption level for male birth cohorts born post-1980, buthehe decrease is not significant for later female cohorts.
While that may be a bit of a letdown for my future biographers (I'm kidding), there is no crisis involved, just a marked increase in the consumption of fatty baked goods and a niggling sense of doubt.
Additionally, developing countries have seen marked consumption increases.
Furthermore, universal screening using AUDIT has highlighted a marked prevalence of high consumption levels and harmful/hazardous/dependent drinking behaviours among male prisoners prior to entry to the study prison (73% having scores indicating AUDs, including 36% 'possibly dependent').
As always, population growth has a marked influence on levels of consumption and the efficiency of resource use.
The International Energy Agency IEAA), in its annual World Energy Outlook, found that coal was "at an inflexion point" with a marked decline in consumption in the biggest market, China.
Chinese consumers are hankering after the good things in life and there is a marked shift in consumption from the mass to premium segments in several categories.
But the austerity and anti-corruption drive of the Chinese president, Xi Jinping, has led to a marked decline in conspicuous consumption and sales of high-end wine.
Recently there is a marked trend to reduce the consumption of red meat, associated with the demand for low-cholesterol foods.
