The phrase "a marked change of" is correct and usable in written English.
It can be used to describe a significant or noticeable alteration in a situation, condition, or behavior.
Example: "There has been a marked change of attitude among the staff since the new management took over."
Alternatives: "a significant shift in" or "a noticeable transformation of".
For there has been a marked change of mood in the Netherlands.
Hillary Clinton has admitted that using a personal email account while she was secretary of state "wasn't the best choice", in a marked change of tack.
Still pessimistic, the later Satires show a marked change of tone and some touches of human kindness, as though he had found some consolation at last.
Not so the Eighth, which, after early criticism from the conductor Hermann Levi, underwent patches of reorchestration, abbreviation and in one instance a marked change of character.
Barring a miraculous recovery in Labour's electoral appeal and a marked change of heart, given the enthusiasm of previous Labour governments and local authorities, contracting volumes are set to grow.
Cameron's remarks earlier this month that it was no longer good enough to say to people "as long as you obey the law, we will leave you alone" were a marked change of tone.
Spencer is still unusually sensitive, said his father, Roger Cambor, a psychiatrist, but added that after months of occupational therapy, "there was a marked change; all of a sudden he could sit in a circle when asked, he settled down, his handwriting got much better".
But the industry's current focus on accessorizing as a form of self expression represents a marked change from most of the last 50 years, when Americans typically strived for a living room of uniform style that looked as if it had been done by a professional.
A G + C skew analysis (data not shown) reveals a marked change in direction of skew just upstream of the single rRNA operon (i.e., in the region of chlI; fig. 1).
Two points stand out from the above findings, (1) riverine flooding is the major type of flood in the study area (2) the nature of the flooding in the area is showing a marked change in terms of its severity having major consequences on the lives and livelihoods of people in the area.
In summary, the data presented show that uremia is accompanied by a marked change in expression of genes involved in a broad range of physiological processes [ 1, 6].
