The phrase "a marked breakdown" is correct and usable in written English.
It can be used to describe a significant or noticeable failure or collapse in a system, process, or relationship.
Example: "The project experienced a marked breakdown in communication, leading to numerous misunderstandings among team members."
Alternatives: "a significant failure" or "a noticeable collapse."
In addition, VEGFA inhibition has been indicated to cause a marked reduction in retinal neovascularization and prevention of the blood retinal barrier breakdown [ 4].
Though it gave Schneider lasting fame, it also started a career marked by breakdowns, drug addiction, a suicide attempt and fractured relationships.
The battle marked a breakdown of a fragile equilibrium that had been established after Kurds and Turks, backed by the United States, helped Syrian rebels oust Islamic State jihadists from a border city last week.
It represents an implicit breakdown of order, a marking of territory by gangs.
Athill will argue that there are two kinds of physical betrayal: the "awful" kind that marks a breakdown in a relationship, and the second kind, an unfaithful act that takes place when someone, "usually the man", succumbs to a little temptation.
Her husband was also on that Crusade, which ended in failure and marked the breakdown of their marriage.
Gallienus' double denarius of copper and silver, leached to give a more silver-rich surface, marked a monetary breakdown, only partially cured when Diocletian and Constantine again made gold the firm basis for supplementary pure silver and abundant copper coinage.
Elsina Wainwright, an analyst at the Australian Strategic Policy Institute who has written on Australia's "near abroad", sees September 11th as instrumental: it helped to focus minds on the dangers of failing states.The Solomons, a collection of 1,000 islands wracked by civil war and political and economic breakdown, marked a key departure for Australia.
People who smoke the most cannabis were found to be the most likely to suffer a psychotic breakdown marked by delusions, hallucinations or disordered thoughts.
