The phrase "a marked affect on" is not correct; it should be "a marked effect on." You can use it when discussing the significant influence or impact something has on another thing.
Example: "The new policy had a marked effect on employee productivity."
Alternatives: "a significant impact on" or "a pronounced influence on."
"But beyond the next year or two, I don't think it is going to have a marked affect on commodity prices.
Previous studies have shown that exposure to bright light can have a marked affect on alertness.
By contrast, interfering with PhuZ filament dynamics has a marked affect on phage DNA positioning (Kraemer et al., 2012).
However, this should not be regarded to have a marked affect on the results, since genetic nature of SNP is generally unlikely to change with age.
Overall we see that changing the substrate from H3 to H3/H4 tetramer or varying whether we limit acetyl-CoA levels or substrate has a marked affect on the ability of both p300 and CBP to acetylate the residues of H3 and H4.
For both microbial and mammalian fermentations, pH is a vital process parameter as it has a marked affect on cell growth rate, viability and product synthesis.
Findings suggest that the brushing protocol had no marked affect on levels of stereotypy.
Finally, we and others have previously reported that modifications in CTT length or amino acid composition can have marked affects on global Env structure and function, including virion incorporation, fusogenicity, and antibody reactivity.
While it is beyond the scope of this paper to understand the biochemical interactions causing the changes in scattering or in cell size, the results demonstrate that frequently used stains have marked affects on the cells and that care must be used when interpreting results of experiments using fluorescent dyes.
IBS affects 10 20% of the population and causes a marked reduction of quality of life in affected individuals.
