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Fibrinogen is a mandatory compound in the coagulation pathway, and the plasma fibrinogen level should be corrected to anticipate clotting.
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Various methods from stoichiometric and constraint-based modeling have been developed to calculate intervention strategies by which a given microorganism can only grow if it synthesizes a desired compound as a mandatory by-product.
For this reason, the activity order of the training set compounds is a mandatory input for hypothesis generation.
Adding GTN and its active compound NO to this trigger list therefore seems to be a mandatory conclusion.
This has been compounded by the fact that detailed work with children has not formed a mandatory part of social work training.
That is a mandatory duty.
"He was a mandatory [challenger].
"That mandatory counseling, it's a mandatory visit.
That charge carries a mandatory prison sentence.
Shakur was handed a mandatory life sentence.
She favors a mandatory balanced budget.
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