Their milk exists in a majority of differentiated variants, and they drink it like water.
Since it is likely a majority of common variants of modest effect have been identified through the application of tagSNP-based microarray platforms (i.e., GWAS), alternative approaches robust to detection of low-frequency (1 5% MAF) and rare (<1%) variants are of great importance.
A majority of the variants was of quantitative type (86%), whereas 14% were qualitative.
A majority of risk variants associated with T2D by GWAS seem to affect islet function (5, 6).
The aim of this project is to establish a platform for genotyping single nucleotide polymorphisms (SNPs, representing a majority of genetic variants) of genes involved in drug metabolism, transport, and targets, and DNA repair, cell signaling, cell cycle, apoptosis [ 11- 14].
Consistent with the recent data published from humans a majority of those variants show close to equal expression of both alleles, with only ~30% showing a marked reduction in the expression of impaired allele.
Patatin-specific hpRNAi effectively suppressed the expression of a majority of patatin variants in potato tubers via the specific degradation of individual mRNAs of the patatin multi-gene family.
It can be seen in (A ) and (B ), that at higher levels of transmission intensity, exposure to the diversity of antigenic types typically shifts towards the younger age classes, and hosts gain high levels of immunity to a majority of the variants earlier on in life.
Clinical samples derived from WNV and DENV infected hosts are typically less genetically heterogeneous compared to samples from a host harboring a chronic infection such as HIV; they are acute diseases and either provide limited time for viruses to develop mutations or undergo very rapid selection, quickly removing a majority of early variants before samples are acquired.
The finding that a majority of these sequence variants resulted in very low levels of NPC1L1 protein in cultured cells is thus congruent with the magnitude of the reduction in LDL-C observed in vivo.
