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By haplotyping a majority of coding and non-coding alleles at the MHC and KIR loci in a single assay, this method has the potential to assist transplantation matching and facilitate investigation of the genetic basis of human immunity and disease.
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In a system where a majority of code status discussions occur between patients and physicians in training, physician unfamiliarity may impact patient knowledge and decision making [ 20].
In contrast, in vivo the bacterium represses a majority of genes coding for nucleotide synthesis and ribonucleotide reductases, which could be connected to the slow replication rate observed compared to in vitro culture conditions.
Recently, Roche Nimblegen has made available a microarray-based sequence capture system that targets the majority of coding exons as listed in the Consensus Coding Sequences (CCDS) collection.
It contains the majority of coding sequence of T. corallinus, a fact that will allow it to be used as a comparison point to other myriapods notably S. maritima —and to the Arthropoda as a whole.
The multiethnic nature of this study was designed to allow for investigating a wide range of risk alleles; however, we found the vast majority of coding variants to be present in more than one population (39 of 40 variants).
This threshold also detects the vast majority of coding exons, yet still detects many noncoding regions.
The provision of chromosomal coordinates for the vast majority of coding region micro-lesions in HGMD is now complete.
Although substitutions comprise the majority of coding variation in the human genome, indels are often clinically relevant.
In these analyses, only genes with a length above 2 kb were kept as shorter genes tend to harbor specific profiles not reflecting the majority of coding sequences, for examples due to shorter (or lack of) introns.
In terms of the contigs themselves, vsp linear arrays accounted for the majority of coding capacity of 56 of the contigs < 10 kb in length, even after some were joined by directed, manual sequencing efforts.
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