The phrase "a major topic for" is correct and usable in written English.
It can be used when discussing a significant subject or issue that is relevant to a particular context or audience.
Example: "Climate change has become a major topic for discussion among world leaders at the summit."
Alternatives: "a key issue for" or "a significant subject for".
By the 1980's urban legends were a major topic for folklore researchers.
A major topic for discussion was the status of a unified Germany.
To increase the thermal stability of protective coatings has always been a major topic for application oriented materials development.
Player troubles away from the field were a major topic for N.F.L. owners at their winter and spring meetings.
Land-use and land-cover change profoundly affect human well-being and, therefore, have become a major topic for society.
The preferences of head and neck cancer patients regarding treatment outcomes are therefore a major topic for patient-centered research.
The above problems with bacterial persisters, also apply to cancer stem cells, and will be a major stumbling block for both fields and a major topic of interest for the future.
STO is a very common substrate for thin-film growth, which is a major topic of interest for electron microscopy, meaning that there will likely be an STO reference region available on many technologically important samples.
The factors that influence the adoption of online gaming are a major topic of concern for academic researchers, online games marketers, and developers alike.
Thermal energy storage in general, and phase-change materials (PCMs) in particular, have been a major topic of research for the last thirty years.
Dressed like a sex symbol, she leans loooow over the Regalia to give it a buff after she's filled up its tank, and a major topic of conversation for Prompto (Bro #3, Noctis' childhood best friend) is how much he fancies her.
