The phrase "a major subgroup of" is correct and usable in written English.
It can be used when discussing classifications or categories within a larger group, particularly in scientific, academic, or organizational contexts.
Example: "The canines are a major subgroup of the family Canidae, which includes wolves, foxes, and domestic dogs."
Alternatives: "a significant subset of" or "a prominent division of".
A major subgroup of patients with schizophrenia lacks insight of having a mental disorder or symptoms of a mental disorder.
A major subgroup of these proteins, the typical 2-Cys peroxiredoxins, can switch between dimers and decameric or dodecameric rings, during the catalytic cycle.
DVA clients are a major subgroup of the Australian population.
Diabetic patients form a major subgroup of patients undergoing cardiovascular interventional procedures.
Minicollagens constitute a major subgroup of these nematocyst-specific extracellular proteins, but another important constituent, dubbed 'cnidoin' is non-collagenous, resembling the spider silk protein spidroin-2.
This study of a major subgroup of applicants in the first year of operation suggests that it has an inherent favourable bias to men and students from a higher socioeconomic class or independent or grammar schools.
This study provides structural information for more than 22 human PTP catalytic domains, thereby completing structural coverage for all major subgroups of the classical PTP family and enabling a comprehensive large-scale structural comparison.
The team's genetic information came from analyses of two particular genes from 230 species representing all major subgroups of modern birds.
Hydroxycinnamic acids (HCAs) possess a simple chemical backbone consisting of a phenylpropanoid C6-C3 structure and are the major subgroup of phenolic acids with ubiquitous distribution in the plant kingdom.
Using a cohort of 321 diagnostic cases of the major subgroup of breast cancer, we found Cn/NFAT pathway activated in ER−PR−HER2− triple-negative breast cancer subtype, whereas its prevalence is less in other subgroups.
The major subgroup of tumor cells was characterized by a high frequency of APC and TP53 mutations while in the minor subgroup, mutations in the cell division cycle 27 (CDC27) and polyadenylate-binding protein, cytoplasmic, 1 (PABPC1) genes were predominant.
