The phrase "a major structural change" is correct and usable in written English.
It can be used when discussing significant modifications or transformations in the organization, design, or framework of something, such as a company, system, or building.
Example: "The company announced a major structural change to improve efficiency and adapt to market demands."
Alternatives: "a significant organizational shift" or "a substantial framework alteration."
So how likely is a major structural change like this, and what might be the consequences?
Increasingly, however, sponsorships are being used strategically inside companies to motivate employees or facilitate a major structural change, such as a merger.
Extremely high pressure, up to 300 GPa, was applied and no significant modification attributable to a major structural change was observed.
Bill Lewis, an analyst at Chase H & Q who rates Seagate a market performer, said he was "extremely cautious" about the industry, which he said was undergoing a major structural change.
I find it hard to believe ministers would have the stomach for introducing such a major structural change, whatever the short-term advantage in meeting Treasury targets, and regardless of what the triennial review might conceivably recommend (paywalled link).
In addition, we found a major structural change in exons 3 4 of the immune-regulatory protein intercellular adhesion molecule 2 (ICAM-2); expression of this variant leads to reduced cell surface expression of ICAM-2.
Morgan is not planning any major structural changes as a result of the layoffs, but the spokesman said the firm would merge its capital markets, debt and equity operations.
While search engines continue to roll out new services and print directories continue to lose customers, we do not see evidence of a 'tipping point' or major structural change in the last few months".
"We won't ourselves be proposing major structural change, not least because the existing structures are only eight years old.
Mallett, who was born in England, said major structural change within the RFU would be a prerequisite for his involvement.
The other major structural change that accompanies this transition is a 10Å translocation of the I domain C-terminal α-helix [5].
