The phrase "a major stimulation" is correct and usable in written English.
It can be used in contexts where you are referring to a significant increase in activity, interest, or response, often in fields like psychology, biology, or economics.
Example: "The new marketing strategy provided a major stimulation to sales, resulting in a record quarter for the company."
Alternatives: "a significant boost" or "a substantial increase".
Third, patients who experienced a smooth extubation maintained a regular respiratory pattern during dressing application, a maneuver that produced major stimulation of the airway.
"Apparently he felt that my alleged irresponsibility lies in the fact that I 'let the nerve-shattering impact of brutality take over the authority of the theme and become the major stimulation an the emotional cathartic of the film,' " Mr. Davis wrote in a letter to The Times after the Crowther review.
The methodology used involves the following steps: (1) Carry out a detailed literature review of the major stimulation challenge facing ultra-tight gas sandstones as well as the fracture fluids currently employed in the industry.
This suggests that, although a functional ABCG5/G8 complex is required for the major stimulation of biliary cholesterol secretion by T3, there is also an additional, ABCG5/G8-independent, mechanism.
Taken together, these results suggest that major stimulation on the AGR2 promoter by hypoxia may act through a hypoxia response region from −937 to −912 bp on the AGR2 promoter.
The multistage hydraulic fracturing has been considered as the major stimulation method used for enhancing well productivity in unconventional low-permeability reservoirs.
This variable response resembles the situation with antihypertensive potassium channel-opening drugs when taken orally; effects range from the major stimulation caused by minoxidil, through little effect in adults with diazoxide but increased growth in children, to no noticeable effect (reviewed in ref. 14).
This study was designed to evaluate the suggestion that during bone vibrator stimulation on skull bone (bone conduction auditory stimulation), a major connection between the site of the bone vibrator and the inner ear is a fluid pathway.
In addition, PGE2 plays a major role in the stimulation of epithelial cell proliferation, inhibition of apoptosis, production of mutagens and stimulation of angiogenesis.
As the blocking with anti-Dectin-1 Ab alone is similar for stimulation with S. Typhimurium and curdlan (55 and 63%), this suggests that a major component of the stimulation by S. Typhimurium is via Dectin-1.
