"a major significant" is a correct and usable phrase in written English.
It is typically used to refer to something that has a large and important impact or effect. For example, "The introduction of the smartphone had a major significant on the way people communicate".
President Bush praised the capture of Mr. Ba'Attash today, telling reporters at the White House that "it was a major, significant find" in the war on terrorism.
Speaking at the World Economic Forum in China, Nouriel Roubini, economist at New York University, described Brexit as "a major significant financial shock" that would create "a whole bunch of economic, financial, political and also geopolitical uncertainties".
"I also think it is terrific that at this particular school we have got a major business – IBM – involved in a very hands-on way so that the graduates of this school will be immediately job-ready and indeed are being offered preferential hiring if you like, preferential entry-level hiring by a major, significant employer," Abbott said.
A major significant stumbling block is Mr Assad's future.
The discovery of rapid synthesis of complex organic solids in the late stages of stellar evolution has led to a new realization that carbonaceous compounds can be a major significant component of interstellar dust.
As expected, E2 treatment induced a major significant decrease of ERα expression and concomitantly of RhoB expression.
Once it's clear that this is a major priority, significant progress can be made.
"For us, we think it's a major, incredibly significant innovation.
The changes are part of a "major and significant" investment pledge from Cardiff's Malaysian owners.
This has provided a major and significant extension of the REA on modeling challenging drying cases.
The club said the changes are part of a "major and significant" investment pledge from the owners.
