The phrase "a major side effect" is correct and usable in written English.
It can be used when discussing the significant negative consequences of a medication, treatment, or action.
Example: "One of the major side effects of this medication is drowsiness, which can impact daily activities."
Alternatives: "a significant adverse effect" or "a serious side effect".
Consider, for example, the FDA's approval in 1976 of the swine flu vaccine, generally perceived to have been a Type I error, because although the vaccine was effective at preventing influenza, it went on to manifest a major side effect that was unknown at the time of approval: 532 cases of paralysis, including 32 deaths, from Guillain-Barré syndrome.
A1 Seizures of Drugs Surging Heightened security after the Sept. 11 attacks has had a major side effect: seizures of illegal drugs along the nation's borders and at its ports of entry have increased greatly.
A major side effect of power dissipation on interconnect lines is an increase in interconnect temperature.
BPs-related osteonecrosis of the jaw (BRONJ) has been characterized as a major side effect of BPs therapy.
Hypotension is considered a major side effect of spinal anaesthesia for caesarean section that can compromise foetal circulation, causing hypoxia and foetal acidosis in the unborn baby [1].
Most sedative drugs have potent hypnotic properties; thus excessive sustained alteration of consciousness is a major side effect of sedation [1].
Osteoradionecrosis of the jaw is a major side-effect of radiotherapy used in the treatment of squamous cell carcinomas of the upper aerodigestive tract.
Clinical application of interleukin (IL -2-based IL -2-basedpy of cancer has been lIL -2-based major simmunotherapyofn as 'cancerary leak syndrome', resulting from nitric oxide (NO) overproduction.
Patient 2: Male, 40 years old, diagnosed at age 36 with chronic B/D coinfection; we started standard peginterferon alpha 2a therapy for 48 weeks; with a major side-effect: Hashimoto thyroiditis in month 3, successfully resolved.
MAO inhibitors were considered in PD therapy as dopamine sparing drugs, however, the first generation of non-selective MAO inhibitors had a major side-effect, known as the 'cheese reaction' (hypertensive crisis because of potentiation of the sympathomimetic activity of tyramine by peripheral inhibition of its MAO metabolism).
Hair transplant has negligible probability of risk, it does not have any major side effect if performed by a specialist.
