The phrase "a major settlement of" is correct and usable in written English.
It can be used when referring to a significant community or population center, often in the context of geography, history, or social studies.
Example: "The region is known for being a major settlement of early European colonists."
Alternatives: "a significant community of" or "a prominent population center of".
Located on the banks of River Vaigai, Madurai has been a major settlement for two millennia and is one of the oldest continuously inhabited cities in the world.
The remains of a major settlement known as Angel Mounds lie east of present-day Evansville.
As a part of a major settlement between the city and U.S. EPA, an underground reservoir system to hold excess effluent during heavy precipitation was constructed (at an estimated cost of $3.9 billion) and completed in 2008.
+39 041 220 1215, cini.it The first major settlement of Venice and a seat of power until the 13th century, this island's wistful, neglected air once inspired the likes of Ernest Hemingway and Harold Pinter.
The major settlement of the time is Fenny Stratford.
A global map of accessibility in 2000, available as a gridded surface at a resolution of 1×1 km with pixel values representing minutes of travel time to the nearest major settlement of population size 50,000 or more, was also utilized for this study [ 39].
A road links the major settlements of Thalang, Phuket, and Ban Rawai.
Major settlements of the valley, which supports sheep, beef, grain, and fruit farming in the upper reaches and vegetable and dairy farming in the delta, include Clyde, Cromwell, Alexandra, Balclutha, and Kaitangata.
They include Grand Bahama, which contains the major settlements of Freeport and West End; Andros (2,300 square miles [6,000 square km]), the largest island of The Bahamas; Abaco, or Great Abaco, (372 square miles [963 square km]); and Eleuthera (187 square miles [484 square km]), the site of one of the early attempts at colonization.
