The phrase "a major research topic" is correct and usable in written English.
You can use it when discussing significant areas of study or investigation within a particular field.
Example: "Climate change has become a major research topic in environmental science over the past decade."
Alternatives: "a key research area" or "a significant research subject".
Hence, the protein function prediction through computational approaches has become a major research topic, which has drawn much attention from researchers in the areas.
Recently, computer-aided diagnosis (CAD) has become a major research topic in medical imaging and diagnosis.
Peer-to-peer (P2P) networks have also become a major research topic over the last few years.
Intelligent Transportation Systems based on Vehicle-2-X communication have been a major research topic for several years.
Technology to assist people in the kitchen has become a major research topic as technology becomes more ubiquitous in the home.
Model-based diagnosis in discrete event systems (DESs) is a major research topic in failure diagnosis, where diagnosability plays an important role in the construction of the diagnosis engine.
PPI appears when two or more proteins bind together and perform a biological function [ 5]. Almost all major research topics in molecular biology involve PPI such as cellular function [ 6], genetic diseases [ 7], conserved patterns [ 8], and homologous relationships [ 9].
This time, the study area was the ice-covered Greenland Sea in the Arctic, and the ecology of the under-ice fauna was the major research topic.
Due to the fact that the tellurite glasses are characterised by high linear as well as nonlinear index, they have become the major research topic of nonlinear optics [3, 4].
Hence, DR was included as one specific major research topic of the integrated EU research project DRUID (Driving under the Influence of Drugs, Alcohol and Medicines; Project No. TREN-05-FP6TR-S07.61320-518404-DRUID) wito the aim to both increase and systematize this knowledge.
