The phrase "a major regulation" is correct and usable in written English.
You can use it when referring to an important or significant rule or law that governs behavior or actions in a specific context.
Example: "The new environmental policy includes a major regulation aimed at reducing carbon emissions from industrial sources."
Alternatives: "a significant regulation" or "a key regulation".
Reversible protein phosphorylation is a major regulation mechanism of fundamental biological processes, not only in eukaryotes but also in bacteria.
It's a major regulation, and it appears to be the future — but what 2015 shows is that, with or without it, we're moving that way anyway.
(Some terminology notes: NPRM is a notice of proposed rulemaking, a draft document explaining a major regulation that is provided and commented on months ahead of the FCC's vote.
Whereas Congress now has to explicitly vote down a regulation by using the Congressional Review Act, under the REINS Act Congress would have to voice approval within 70 days if a major regulation is to take effect.
Vettel has been out-qualified six times in eight races so far and is behind Ricciardo in the championship as he struggles to come to terms with the new generation of turbo hybrid F1 cars following a major regulation change.
Pirelli is also disagreeing with the teams over its desire to do more testing to prepare tyres for next season, when the cars and engines will be different following a major regulation change.
We systematically review a dozen major regulations issued between 2009 and 2011, with a predominant focus on environmental regulations, to see whether this expectation is met.
Lysine acetylation of cytoplasmic proteins in macrophages is emerging as a major cell regulation mechanism after nTiO2 exposure.
He has proposed weakening a major Obama regulation requiring automakers to nearly double the fuel economy of passenger vehicles by 2025.
In this way, either the House or the Senate could easily scuttle a major new regulation — one that requires food producers to sanitize their tools, for example — simply by doing nothing.
Republicans just repealed a major safety regulation issued by former President Barack Obama.
