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The phrase "a major reduction of" is correct and usable in written English.
It can be used when discussing a significant decrease in quantity, size, or intensity of something.
Example: "The company announced a major reduction of its workforce due to budget cuts."
Alternatives: "a significant decrease in" or "a substantial cut to".
Exact(53)
We have also seen a major reduction of cost in all forms of energy.
HSA and BSA conformations were altered by a major reduction of α-helix upon SFN interaction.
The procedure is flexible and accurate and leads to a major reduction of the simulation time.
could possibly lead to a major reduction of political violence". Violence, Sharp says, is "your enemy's best weapon". Dictators will only try to crush rebellions.
Ferretti, E. et al. Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype.
These results show a major reduction of sound and vibration levels in the passenger compartment of the vehicle.
Similar(7)
"The loss of Quincy is a major reduction in the size of the mobilization base and our capability of meeting wartime demand," Babbin said.
"For every hour we see a reduction in alcohol trading in the Kings Cross and CBD area, we are confident of seeing a major reduction in the amount of alcohol-related presentations that will come through our emergency department doors," Winder said in a statement.
Our finding of a major reduction in deaths related to overdose of methadone raises the question of whether other changes in treatment practice could achieve even greater reductions in deaths related to overdose of methadone and other opioids.
DOI: http://dx.doi.org/10.7554/eLife.12177.005 In the SREBP-2 cleavage assay, the addition of 10% FCS led to a major reduction in the amount of nuclear SREBP-2.
Knockdown of either RRS1 or BXDC1 resulted in a major reduction in the amount of RPL5 in the nucleolus.
More suggestions(15)
a broad reduction of
a major drawdown of
a major decrease of
a great reduction of
a serious reduction of
a large reduction of
a momentous reduction of
a severe reduction of
a considerable reduction of
a principal reduction of
a substantial reduction of
a large scale reduction of
a major driver of
a major point of
a major component of
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com