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The phrase "a major rationale" is correct and usable in written English.
It can be used when discussing the primary reason or justification for a decision, action, or belief.
Example: "The need for sustainable practices is a major rationale behind the company's new environmental policy."
Alternatives: "a key reason" or "a primary justification."
Exact(16)
Both sides cited economies of scale – significantly, their combined media-buying power – as a major rationale for the deal.
A major rationale for the proposed merger with Compaq, announced in September, was management's contention that the combined enterprise could trim costs by $2.5 billion, mainly by eliminating overlapping operations.
And Obama has made it clear that a major rationale for the TPP is not promoting shared prosperity – the idealistic motivation that lay behind the birth of the Doha round – but creating a political and economic counterweight to the might of China.
But in April, when Mr. Obama released the Bush administration's legal opinions, which included extensive descriptions of the C.I.A.'s interrogation methods, the agency lost a major rationale for withholding the other documents, and it agreed to review them again for possible release.
A major rationale is that the social democratic developmental model links democracy and development in mutually reinforcing ways: a sustainable democracy requires development and vice versa.
A major rationale was to try to understand how much residual stress will be relieved due to the removal of the strip sample from the pipe.
Similar(44)
The other major rationale for a soul-based theory of life's meaning is that a soul is necessary for perfect justice, which, in turn, is necessary for a meaningful life.
After two recent conflicts – in Iraq and Afghanistan – in which, many allege, a secure energy supply was the major rationale for US involvement, the controversial practice known as hydraulic fracturing, or fracking, now offers the prospect of North American energy independence.
One major rationale to use a biclustering approach is that genes may exhibit correlated expression profiles under certain conditions, but not in other conditions [ 18].
A major underlying rationale for imposing a substantial fine in a case like this is it's deterrent value".
A major underlying rationale for imposing a substantial fine in a case like this is its deterrent value".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com