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The phrase "a major problem after" is correct and usable in written English.
It can be used to indicate a significant issue that arises following a specific event or situation.
Example: "The team faced a major problem after the unexpected budget cuts were announced."
Alternatives: "a significant issue following" or "a critical challenge post".
Exact(9)
However, stenosis caused by neointimal hyperplasia, vascular remodeling and thrombosis is still a major problem after endocoronary stent procedures.
Hemorrhage continues to be a major problem after cardiac surgery despite the routine use of antifibrinolytic drugs, with striking inter-patient variability poorly explained by already known risk factors.
Finally, if this is a major problem after we've done our first season of testing this year, we can look at making the wheels from steel if we need to - we know that they can be made thin enough, and steel should be more than hard enough.
Transportation can severely restrict operations and has been noted previously as a major problem after the tsunami (19, 47, 48).
LTP is a major problem after local ablative therapies, especially in large tumors, as confirmed by this study demonstrating a local recurrence rate of 38%.
Dislocation remains a major problem after primary total hip arthroplasty (THA), and has a considerably negative effect on the quality of life after THA, especially if it is recurrent (Enocson et al. 2009b).
Similar(51)
This is a major problem because after awhile no one wants to really talk to you due to the echo.
Identify theft is a major problem in America, and, after the Target breach last year, we knew something had to be done.
A major problem in cortical functioning after, for example, a stroke, arises from over-activation in the periphery of the lesion (e.g., ischaemic penumbra).
Creeping environmental changes are incremental changes in conditions that cumulate to create a major problem, apparent or recognized only after a threshold has been crossed (Glantz 1994a, 1994b).
Postoperatively, HCC recurrence in residual liver is a major problem in patients 1 year after surgical resection.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com