Sentence examples for a major pathogenic determinant from inspiring English sources

The phrase "a major pathogenic determinant" is correct and usable in written English.
It can be used in scientific or medical contexts to refer to a significant factor that contributes to the pathogenicity of an organism or disease.
Example: "The researchers identified a major pathogenic determinant that influences the severity of the infection."
Alternatives: "a key pathogenic factor" or "a significant disease determinant."

Exact(1)

Since Nef-induced exosomes are able to induce such bystander T-cell killing [ 116], triggering exosome release from HIV-1 infected cells may represent a major pathogenic determinant of this viral protein.

Similar(59)

Charcoal rot caused by Macrophomina phaseolina in castor is one of the major pathogenic determinants for extreme yield loss.

These results suggest that autoantibody-mediated ADAMTS13 clearance is a major pathogenic mechanism and determinant of disease severity.

Oxidative stress is a major pathogenic mechanism of lead neurotoxicity.

Cardiomyocyte loss is a major pathogenic mechanism leading to heart failure.

Immunological dysregulation is now recognised as a major pathogenic event in sepsis.

We suggest that Nlrp3-mediated IL-1β activation in sepsis is a major pathogenic mechanism in inflammatory muscle atrophy.

Immune reactions against host liver antigens are believed to be a major pathogenic mechanism.

Hypoxia plays a major pathogenic role in diabetic nephropathy (DN).

Immunoparalysis has been convincingly established as a major pathogenic mechanism in sepsis (Hotchkiss et al, 2013).

These data confirm that TNF, apparently, is not a major pathogenic factor in pSS.

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