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1 13 17–31 According to Staines and Cleland, 29 "RA represents a major overestimation bias, is a frequent phenomenon applied directly to both primary studies and meta-analyses and additionally meta-analysts, like primary investigators, can exhibit allegiance to a hypothesis being tested".
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This would be a major misjudgment, one based on their overestimation of the risks posed by reform.
This paper also shows that ignoring the existence of a major gene in genetic evaluation could lead to a large overestimation of polygenic breeding values for prolificacy.
The study by Duffy and Parmar represents a major advance because it calculates the length of follow-up time necessary to preclude any overestimation of overdiagnosis [ 1].
Despite reported high correlation between the SWA and indirect calorimetry the large bias (overestimation) observed during a variety of common activities of daily living represents a major concern for the validity in patients with hip OA.
Thus, although the effect of measurement error and selective underestimation or overestimation of dietary intake can never be excluded, data inaccuracy is unlikely to have had a major impact on our findings.
Spurious associations between single nucleotide polymorphisms and phenotypes are a major issue in genome-wide association studies and have led to underestimation of type 1 error rate and overestimation of the number of quantitative trait loci found.
Our data display a well-known distortion between pollen taxa percentages calculated from palynological slides and current vegetation cover on land, with a particular overestimation of arboreal taxa as well as an underestimation of herbaceous ones, especially of cereal crops that represent a major component of the regional continental vegetation.
What makes a major a major?
A major, major talent.
"This is a major, major issue".
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