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The phrase "a major link between" is correct and usable in written English.
It can be used to describe a significant connection or relationship between two or more entities, concepts, or phenomena.
Example: "The study highlights a major link between diet and mental health, suggesting that nutrition plays a crucial role in emotional well-being."
Alternatives: "a significant connection between" or "a key relationship between".
Exact(24)
"There is a major link between our emotions and the food choices we make.
If so, this forgotten Sarasvati might provide a major link between Vedic and Indus Valley cultures.
Churchill and Nye, Mao and Nixon, Khrushchev and De Gaulle - a major link between the Commons and its past is about to be severed.
But with increased security, and additional streets blocked off, there are bound to be traffic snarls, particularly on Interstate 80, a major link between the airport and downtown, as well as the main route to four mountain venues.
It was not until the mid-13th century that the pass attained any importance as a route, and it was only when Napoleon built (1800 07) a carriage road through the Gorge of Gondo that the pass began to compete with the other Alpine passes as a major link between central and southern Europe.
The Suez Canal, which was closed at the time of the Six-Day War with Israel in 1967, was reopened in 1975 and was subsequently expanded to accommodate larger ships; it serves as a major link between the Mediterranean and Red seas.
Similar(35)
A major link exists, for example, between the aircraft structure and aerodynamics.
Could the well-documented stage-dependent susceptibility to physicochemical agents during developmental stages (Degitz et al. 2000; Fort et al. 2004; Greulich and Pflugmacher 2003; Herkovits and Fernandez 1979; Herkovits et al. 1997; Kast-Hutcheson et al. 2001; Rutledge 1997) provide a second major link between ontogenesis and the adaptation of life forms to their environment?
Information derived by comparison of gene expression and SEREX-ovarian datasets, although expanded by coregulation and network analysis, indicated no major link between local abundance of a protein and its potential for autoantigenicity, at least at the level of given datasets.
Roads became the major link between the urban areas and the rural hinterlands, although they were developed in colonial times as a subsidiary to the railway line running from Mombasa to the western parts of the country.
The Federal Vocational Baccalaureate constitutes the major link between the academic and vocational tracks in the Swiss educational system.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com