Your English writing platform
Discover LudwigSuggestions(5)
The phrase "a major limitation when" is correct and usable in written English.
It can be used to introduce a discussion about a significant drawback or restriction that occurs under certain circumstances.
Example: "A major limitation when conducting this type of research is the lack of available data."
Alternatives: "a significant drawback when" or "a key constraint when".
Exact(17)
Hence, this presents a major limitation when attempting to develop antibodies against challenging target antigens.
As a result, these methods have slow temporal resolution which is a major limitation when investigating live-cell dynamics.
The small sample size in our study is a major limitation when screening for low frequency SNPs.
Microdialysis contains a major limitation when estimating data because only an approximation can be stated.
This is a major limitation when it comes to comparing studies and developing biomarkers.
The scarcity of glaucophyte genomic data has been a major limitation when testing the monophyly of the Archaeplastida.
Similar(43)
This fact has to be considered as one major limitation when discussing trainees' early ADR values.
The specificity of the immobilized antibody on the ELISA plate is certainly one major limitation when assaying small numbers of samples.
Major limitations when decreasing electrode size in dense arrays are increased noise level and low charge injection capability.
Nevertheless, low cell seeding efficiency and non-uniform distribution of cells remain major limitations when using such types of scaffold.
Both study designs had major limitations when addressing infection risk.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com