Sentence examples for a major issue since from inspiring English sources

The security of general aviation airplanes has been a major issue since four airliners were hijacked on Sept. 11.

This is a major issue since woody samples that contain any salts such as ILs can indeed be quite challenging from the analytic point of view.

The shift in priorities, documented in a number of studies, has become a major issue since a new Governor, Gray Davis, and a new Legislature took office.

Human Machine Interaction HMII) has been a major issue since the very early phase of car development.

Human Machine Interaction HMIinitiallyalimitedited only to the primary in-vehicle commands, has been a major issue since the beginning.

The different simulations suggest that the visual obstruction of the surgical burr was not a major issue, since no discomfort was reported by surgeons using the simulator.

Emigration from Cuba to the United States has been a major issue since 1980, when some 125,000 Cubans crossed the Florida Straits to the United States during what became known as the "Mariel boatlift" (so named because many of the boats departed from Mariel, a small port west of Havana).

Pre-operative diagnosis of SSC tendon tears is therefore a major issue, especially since a lesion of the SSC tendon will have an impact on treatment, surgical approach, and post-operative functional prognosis [6].

Although the quantity of recombinant human IL-1ra produced by S. gordonii is not as large as that reported in other studies [ 48, 49], high productivity is not a major issue here, since this work aims at developing a mucosal drug delivery system rather than a system for large-scale production of drugs.

Factory safety has been a major issue in Bangladesh since the collapse of the Rana Plaza clothing manufacturing complex in April 2013 that left more than 1,100 people dead, making it one of the worst industrial accidents in history.

Water concerns dominated discussions, likely due to the severity of the El Niño drought that was in effect, although an "over time analysis" suggested that this has been a major issue at least since the 1950s.