The phrase "a major issue in the development" is correct and usable in written English.
It can be used when discussing significant problems or challenges that arise during the process of development, whether in projects, software, or other contexts.
Example: "One of the major issues in the development of the new software was the lack of adequate testing before the launch."
Alternatives: "a significant challenge in the development" or "a key problem in the development".
Architectural integration is a major issue in the development and spreading of solar thermal technologies.
Long-term stability is a major issue in the development of new catalysts and in the improvement of existing catalysts.
Given that smart home applications are based on the integration of many heterogeneous devices in the same network, the lack of interoperability can become a major issue in the development of advanced services.
In this regard, the challenges and limitations of the signal processing techniques are summarized as follows: Efficient processing: Efficient signal processing is a major issue in the development of the future grid due to the interconnection of various technologies and diverse nature of the smart grid.
Targeted gene therapy is a major issue in the development of gene therapy towards clinical trials.
Efficient electron transfer between redox enzymes and electrodes is a major issue in the development of biosensors and biofuel cells.
The negative symptoms of schizophrenia are a major factor in interpersonal and social isolation and the impairment of quality of life, and thus represent a major issue in the field of development of new therapeutic strategies, notably drug strategies.
A major issue in the process of accelerated atherosclerosis in RA is the development of endothelial dysfunction, an early step in the development of atherosclerosis.
A major issue in the application of computers to future catalytic research and development will be constructing user-friendly systems for computer-aided design of catalytic reactions and catalysts.
Downtown construction was a major issue in the recent City Council election, one that saw two of the architects of the development plan leave the dais — one involuntarily.
With the rapid increase of large scale shopping developments in Eastern European Countries, retail design has become a major issue in the professional practice.
