Sentence examples for a major issue however from inspiring English sources

Since the association between TLF and working hours after controlling for several individual and job-related factors turns out to be almost absent, this does not seem to be a major issue, however.

A major issue, however, is that no general overview is available to help structural designers in determining design strength values for friction stir welded joints or their dependence on material type or process parameters.

Power consumption in irreversible QCA logic circuits is a vital and a major issue; however in the practical cases, this focus is mostly omitted.The complete power depletion dataset of different QCA multiplexers have been worked out in this paper.

This was not a major issue however, as the +2 boasted a menu system, almost identical to the ZX Spectrum 128, where one could switch between 48k BASIC programming with the keywords, and 128k BASIC programming in which all words (keywords and otherwise) must be typed out in full (although the keywords are still stored internally as one character each).

These run neck-and-neck or a close second to XNU (that's what they call the OS X kernel. Who knew?) One major issue, however, is the graceful mounting and unmounting of external devices.

There was one major issue, however, which was common to all participants: the view that hypertension is a gamble, which can either have or not have serious effects in the future.

On two other major issues, however, the United States and North Korea remained far apart.

On most major issues, however -- clean air, clean water, the protection of the public lands from commercial exploitation -- he has retreated or signaled retreat from the policies of his predecessor.

However, a major issue which has not yet come into the focus is personalizing intra-operative imaging, allowing for optimal treatment.

We note that the nonspecificity of pollutants impacting asthma morbidity suggests this is not a major issue in our study; however, variable weighting or selection strategies could offer opportunity for improvement [ 23].

However, a major issue in this procedure is dealing with occlusion and perspective effects.