The phrase "a major involvement of" is correct and usable in written English.
It can be used when discussing the significant participation or engagement of a person, group, or factor in a particular context or situation.
Example: "The project was successful due to a major involvement of community members in the planning process."
Alternatives: "a significant role of" or "a substantial participation of".
Our data point to a major involvement of serine proteases and a non-thermolysin-like zinc metalloprotease in microgametocyte exflagellation.
FTIR analysis confirmed a major involvement of the participation of amide, amines, ketones and primary alcohol groups during Ce(III) biosorption.
FTIR analysis confirmed a major involvement of the participation of amide, amines, alkines, aliphatic compounds and alkyl groups during La III) biosorption.
This biological effect was inhibited after heat inactivation or pretreatment with RNAse, indicating a major involvement of protein and mRNA components in the observed phenomena [13].
The slow kinetics of hydroxyl radical release (the small amount of radicals generated in the first minutes of incubation with H2O2 followed by a progressive increase; Table 5) observed for all INGV samples could suggest a major involvement of iron in the oxidized state.
This Ch-mediated GABA release was not inhibited in the presence of TTX, therefore excluding a major involvement of the voltage dependent sodium channels.
The lack of any major involvement of DNA-PKcs in NHEJ in hESCs was supported by siRNA-mediated DNA-PKcs knockdown.
These experiments suggest a direct and major involvement of SPRR proteins in intracellular ROS detoxification.
In the SCAT a larger number of genes were up- or down-regulated by HFD than in VAT, but most of these genes were regulated irrespective of body weight gain and GSEA suggested a less active adipogenesis and no major involvement of the tissue stroma.
Although the 5′UTR variant within KLHL9 was absent in a French control population, we ruled out major involvement of KLHL9 in the susceptibility to melanoma by screening the entire coding sequence of the candidate gene in a panel of 42 high-risk CMM families.
Spondyloepiphyseal dysplasia Omani type, which is characterized by severe chondrodysplasia with major involvement of the spine, is caused by a loss-of-function mutation in C6ST1 [ 108– 108].
