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The phrase "a major insight" is correct and usable in written English.
It can be used when discussing a significant understanding or realization gained from analysis or experience.
Example: "After reviewing the data, we discovered a major insight that could change our approach to the project."
Alternatives: "a significant revelation" or "a key understanding."
Exact(18)
Researchers have now gained what seems to be a major insight into how nature builds brains of such different capabilities.
In that sense it's a major insight in that it gives us a better notion of van Gogh the artist.
"If right, this is clearly a major insight into gravity and quantum mechanics," an enthusiastic Dr. Susskind said.
"Her drawing conveys a lot of the underlying feeling of what's going on in the same way a movie can have a shot without dialogue that's a major turning point or a major insight into a character.
No longer content to lurk in the middle of sentences, it has jumped to the beginning, where it can portend many things: transition, certitude, logic, attentiveness, a major insight.
The web app's design was based on a major insight from Robinhood's research.
Similar(42)
As a first major insight of the conducted study, it can be ascertained that there are preferences for existing AIT administration forms in place.
This is just one of a few major insights in a study that the authors admit is merely a first and perhaps imprecise step in testing the hypothesis.
Unlike other large-scale cancer genomics efforts, identifying and characterizing the tumors from even a few extraordinary responses can lead to major insight and advances in cancer therapy.
This level of regulation has not been described previously and is a major new insight that arises from our study.
Our finding that allogeneic MSC injections in patients with both ischemic and non-ischemic HF results in an improvement in endothelial function, specifically by restoring EPC function and FMD and reducing VEGF levels towards normal, offers a major new insight into the mechanisms of action of MSCs.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com