The phrase "a major increase of" is correct and usable in written English.
It can be used when discussing a significant rise in quantity, value, or intensity of something.
Example: "The report indicated a major increase of sales in the last quarter, surpassing all previous records."
Alternatives: "a significant rise in" or "a substantial growth of".
The new data show that in Brooklyn, Queens and the Bronx -- counties with a major increase of immigrants -- median income fell sharply.
Hydrogenation causes a color change from white to cyan and a major increase of photocatalytic activity.
Furthermore, a major increase of micromotion was measured at the bone-cement interface (+706%).
Spurious isotonic hyponatremia represents a phenomenon which arises in case of a major increase of the solid fraction of the plasma stemming from either a major increase of lipids or proteins.
This study demonstrates that when applying MLPA in a routine cytogenetic diagnostic setting, a major increase of the diagnostic yield can be achieved.
These data underlined that inflammatory or ischemic acute events are all characterized by a major increase of NAA leakage following acute neuronal damage, whereas in neurodegenerative processes the NAA increase is less, following a slower but progressive pathological neuronal impairment.
Data from Nigeria were specifically excluded from the analysis because of a major increase in reported cases of neonatal tetanus in 2013, the reasons for which were unclear.
Obesity is fuelling a major increase in the number of cases of kidney cancers diagnosed in Britain, experts say.
Ethiopia, having experienced a major increase in the burden of TB, presents one of the most serious public health challenges.
Effective global stimulus must involve a major increase in the resources of global institutions and the role of new big players.
There was a "major increase" in the number of journalists kidnapped in 2010, with Afghanistan a hot spot of trouble.
