The phrase "a major implication on" is not correct in standard English; it should be "a major implication for" or "a major implication of." You can use it when discussing the consequences or effects of a particular situation or decision, but it needs to be rephrased for correctness.
Example: "The new policy has a major implication for employee productivity."
Alternatives: "a significant impact on" or "a major consequence of".
However, the overall observations suggest a major implication of fructose on changes in brain activity similar to those observed with addictive drugs, which may lead to an altered reward response to palatable food [ 126].
A major implication of this study is on sensitivity of breast cancer cells to chemotherapy.
We also explore how farmers respond to increased volatility in output prices, which we consider as an example of a large scale disturbance with a potentially major implication on the spatial conditions of the network of nature areas.
Although Google's decision is commendable, it is unlikely to have any major implications on China's extensive filtering practices.
The results of this variation have a direct impact on two key parameters of the CMOS transistor: threshold voltage and gate length, which have major implication on the core speed and power.
It should be noted here as well that hydrogen-bonding interactions to nonheme iron(IV -oxo complexes were found to decrease the catalytIV -oxovity of the oxidant,[ 16] so that seemingly innocomplexes interactions can have major implications on a catalytic reaction center.
What is clear is that the current position is unsatisfactory: delays (or perceived delays) in diagnosis can have major implications on acceptance of a cancer diagnosis and a patient and family's subsequent healthcare-seeking behaviour.
It was rescheduled for Sunday as part of a day-night doubleheader that could have major implications on the National League East race.
Such a substantial upward revision of abundance has major implications on the perceived functional relevance of stromal cells and their proposed mode of action.
Diabetic sensorimotor polyneuropathy (DSP) represents a diffuse symmetrical and length-dependent injury to peripheral nerves that has major implications on quality of life, morbidity, and from a public health perspective, costs (1, 2).
