The phrase "a major implication of" is correct and usable in written English.
It can be used when discussing the significant consequences or effects that arise from a particular situation, study, or argument.
Example: "One major implication of the research findings is that we need to reconsider our approach to climate change."
Alternatives: "a significant consequence of" or "a key effect of".
A major implication of this analysis is that, if the majority of cancers are not likely to be preventable, greater efforts need to be directed at early detection so that cancers can be caught early and treated when treatment is likely to be most effective.
A major implication of these data is that the inability to internalize PEG-HCCs allows key immune functions of macrophages to remain unaltered.
A major implication of our study is that we now have validated a new method for evaluating the effect of drugs and environmental toxicity on human embryonic development.
A major implication of these findings is that professional support focusing on instructors' beliefs is of crucial importance to unlock blended learning's full potential.
A major implication of this analysis is that the Antikythera Mechanism of the 2nd century BCE modeled the anomalistic motion of the Moon more accurately than Ptolemy's account of Hipparchus's theory of the 2nd century CE.
A major implication of this phenomena is that liquid will spread more on less wettable (but porous) surfaces in comparison to more wettable (but nonporus) surfaces and a reinterpretation of experiments involving spreading of liquid over porous solids is required.
While the difference is relatively small, it has a major implication on the practicality of the standard single gene test for identifying the driver genes.
We understand these results to hold a major implication for the design of the prevention strategies, in which the areas of priority clearly need special emphasis.
The observations reported here have a major implication for the use of specific PBH capping agents in nanomaterial science.
In spite of these limitations we strongly feel that the peak UPCR in dengue should be practiced by primary care physicians when they encounter suspected cases of dengue as the onset of proteinuria and subsequent demonstration of peak UPCR could have a major implication in identification of incipient DHF and stratification of management strategy for such cases.
Importantly, mitochondrial toxicity is a major implication in the failure of chemotherapeutic agents in the late stages of drug development [ 93].
