Sentence examples for a major hypothesis from inspiring English sources

In addition to avoiding speculation, avoid phrases like "interestingly, we found that…", unless that interestingness can be concretely justified e.g., the result contradicts a major hypothesis, or past findings in the field.

A major hypothesis regarding the poor efficacy of BCG vaccination in developing countries is that intense exposure to environmental mycobacteria reduces the immunogenicity and efficacy of BCG[4], [5].

Even if the basis for cyclin E prognostic significance is not known, a major hypothesis is that cyclin E overexpression reflects alterations in any part of the p16 cyclinD Rb E2F pathway, which is mutated in most cancers.

A major hypothesis suggests that phenotypic plasticity is favored over local adaptation when the spatial scale of dispersal spans several environmental states (Sultan and Spencer, 2002).

It is a major hypothesis of disease pathogenesis that causative mutations within genes might be within very similar or even identical genetic pathways.

Importantly, vasospasm in the occipital hemisphere in patients who have migraine with aura, and the subsequent reduction in the blood flow, is a major hypothesis in the explanation of visual aura and headache.

In the DIGRE model, the major hypothesis is a genomic "residual effect".

This data was included to address the major hypothesis that a second round of ubiquitination can occur at the TGN.

The major hypothesis concerning a potential benefit of tomato products on prostate cancer risk is that lycopene prevents oxidative DNA damage in prostate tissue by reducing exposure to cellular free radicals.

Our major hypothesis is that a transient low pH environment resulting from gastric aspiration adversely affects alveolar macrophage (aMØ) antimicrobial function.

Our major hypothesis is that a different prognostic significance of Skp2 in men and women exists and is related to diverse gender expressions of ER and PGR.